Научные интересы

Структура и функции РНК-содержащих клеточных машин, функциональные свойства и механизмы регуляции теломеразных РНП-комплексов и некодирующих РНК.

Научные публикации

•‎ Shliapina V.L., Koriagina M.S., Vasilkova D.V., Govorun V.M., Dontsova O.A., Rubtsova M.P. Human Telomerase RNA Protein Encoded by Telomerase RNA is Involved in Metabolic Responses. Front Cell Dev Biol. 2021. V.9: 754611. doi: 10.3389/fcell.2021.754611.
•‎ Osterman IA, Wieland M, Maviza TP, Lashkevich KA, Lukianov DA, Komarova ES, Zakalyukina YV, Buschauer R, Shiriaev DI, Leyn SA, Zlamal JE, Biryukov MV, Skvortsov DA, Tashlitsky VN, Polshakov VI, Cheng J, Polikanov YS, Bogdanov AA, Osterman AL, Dmitriev SE, Beckmann R, Dontsova OA, Wilson DN, Sergiev PV. Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel. Nat Chem Biol. 2020 16(10):1071-1077. doi: 10.1038/s41589-020-0578-x.
•‎ Laptev I, Shvetsova E, Levitskii S, Serebryakova M, Rubtsova M, Zgoda V, Bogdanov A, Kamenski P, Sergiev P, Dontsova O. METTL15 interacts with the assembly intermediate of murine mitochondrial small ribosomal subunit to form m4C840 12S rRNA residue. Nucleic Acids Res. 2020 48(14):8022-8034. doi: 10.1093/nar/gkaa522.
•‎ Savelyev NV, Shepelev NM, Lavrik OI, Rubtsova MP, Dontsova OA. PARP1 Regulates the Biogenesis and Activity of Telomerase Complex Through Modification of H/ACA-Proteins. Front Cell Dev Biol. 2021 9:621134. doi: 10.3389/fcell.2021.621134.
•‎ Averina OA, Permyakov OA, Grigorieva OO, Starshin AS, Mazur AM, Prokhortchouk EB, Dontsova OA, Sergiev PV. Comparative Analysis of Genome Editors Efficiency on a Model of Mice Zygotes Microinjection. Int J Mol Sci. 2021. 22(19):10221. doi: 10.3390/ijms221910221.
•‎ Laptev I, Shvetsova E, Levitskii S, Serebryakova M, Rubtsova M, Zgoda V, Bogdanov A, Kamenski P, Sergiev P, Dontsova O. METTL15 interacts with the assembly intermediate of murine mitochondrial small ribosomal subunit to form m4C840 12S rRNA residue. Nucleic Acids Res. 2020 48(14):8022-8034. doi: 10.1093/nar/gkaa522.
•‎ Rubtsova M, Dontsova O. Human Telomerase RNA: Telomerase Component or More? Biomolecules. 2020 10(6):873. doi: 10.3390/biom10060873.
•‎ Osterman IA, Chervontseva ZS, Evfratov SA, Sorokina AV, Rodin VA, Rubtsova MP, Komarova ES, Zatsepin TS, Kabilov MR, Bogdanov AA, Gelfand MS, Dontsova OA, Sergiev PV. Translation at first sight: the influence of leading codons. Nucleic Acids Res. 2020 48(12):6931-6942. doi: 10.1093/nar/gkaa430.
•‎ Komarova ES, Chervontseva ZS, Osterman IA, Evfratov SA, Rubtsova MP, Zatsepin TS, Semashko TA, Kostryukova ES, Bogdanov AA, Gelfand MS, Dontsova OA, Sergiev PV. Influence of the spacer region between the Shine-Dalgarno box and the start codon for fine-tuning of the translation efficiency in Escherichia coli. Microb Biotechnol. 2020. 13(4):1254-1261. doi: 10.1111/1751-7915.13561.
•‎ Pletnev P, Guseva E, Zanina A, Evfratov S, Dzama M, Treshin V, Pogorel'skaya A, Osterman I, Golovina A, Rubtsova M, Serebryakova M, Pobeguts OV, Govorun VM, Bogdanov AA, Dontsova OA, Sergiev PV. Comprehensive Functional Analysis of Escherichia coli Ribosomal RNA Methyltransferases. Front Genet. 2020. 11:97. doi: 10.3389/fgene.2020.00097

Премии и награды

•‎ Премия Европейской Академии молодым ученым (1999).
•‎ Соросовский профессор (1999, 2000).
•‎ Премия имени А. Н. Белозерского (2016).
•‎ Премия имени А. Н. Баха (2020).

Персональные профили исследователя

•‎ Web of Science: T-6072-2019.
•‎ Scopus: 7004105777.
•‎ РИНЦ: 81547.