Научные интересы

Создание соединений для высокоточной диагностики и эффективной терапии онкологических заболеваний.

Научные публикации

•‎ Deyev SM, Waibel R, Lebedenko EN, Schubiger AP, Plückthun A. Design of multivalent complexes using the barnase*barstar module. Nat Biotechnol. 2003 Dec;21(12):1486-92. doi: 10.1038/nbt916.
•‎ Nikitin MP, Shipunova VO, Deyev SM, Nikitin PI. Biocomputing based on particle disassembly. Nat Nanotechnol. 2014 Sep;9(9):716-22. doi: 10.1038/nnano.2014.156.
•‎ Nikitin MP, Zelepukin IV, Shipunova VO, Sokolov IL, Deyev SM, Nikitin PI. Enhancement of the blood-circulation time and performance of nanomedicines via the forced clearance of erythrocytes. Nat Biomed Eng. 2020 Jul;4(7):717-731. doi: 10.1038/s41551-020-0581-2.
•‎ Mitiouchkina T, Mishin AS, Somermeyer LG, Markina NM, Chepurnyh TV, Guglya EB, Karataeva TA, Palkina KA, Shakhova ES, Fakhranurova LI, Chekova SV, Tsarkova AS, Golubev YV, Negrebetsky VV, Dolgushin SA, Shalaev PV, Shlykov D, Melnik OA, Shipunova VO, Deyev SM, Bubyrev AI, Pushin AS, Choob VV, Dolgov SV, Kondrashov FA, Yampolsky IV, Sarkisyan KS. Plants with genetically encoded autoluminescence. Nat Biotechnol. 2020 Aug;38(8):944-946. doi: 10.1038/s41587-020-0500-9.
•‎ Zelepukin IV, Yaremenko AV, Ivanov IN, Yuryev MV, Cherkasov VR, Deyev SM, Nikitin PI, Nikitin MP. Long-Term Fate of Magnetic Particles in Mice: A Comprehensive Study. ACS Nano. 2021 Jul 12. doi: 10.1021/acsnano.1c00687.
•‎ Shipunova VO, Komedchikova EN, Kotelnikova PA, Zelepukin IV, Schulga AA, Proshkina GM, Shramova EI, Kutscher HL, Telegin GB, Kabashin AV, Prasad PN, Deyev SM. Dual Regioselective Targeting the Same Receptor in Nanoparticle-Mediated Combination Immuno/Chemotherapy for Enhanced Image-Guided Cancer Treatment. ACS Nano. 2020 Oct 27;14(10):12781-12795. doi: 10.1021/acsnano.0c03421.
•‎ Aghayeva UF, Nikitin MP, Lukash SV, Deyev SM. Denaturation-resistant bifunctional colloidal superstructures assembled via the proteinaceous barnase-barstar interface. ACS Nano. 2013 Feb 26;7(2):950-61. doi: 10.1021/nn302546v.
•‎ Guryev EL, Volodina NO, Shilyagina NY, Gudkov SV, Balalaeva IV, Volovetskiy AB, Lyubeshkin AV, Sen' AV, Ermilov SA, Vodeneev VA, Petrov RV, Zvyagin AV, Alferov ZI, Deyev SM. Radioactive (90Y) upconversion nanoparticles conjugated with recombinant targeted toxin for synergistic nanotheranostics of cancer. Proc Natl Acad Sci U S A. 2018 Sep 25;115(39):9690-9695. doi: 10.1073/pnas.1809258115.
•‎ Serebrovskaya EO, Edelweiss EF, Stremovskiy OA, Lukyanov KA, Chudakov DM, Deyev SM. Targeting cancer cells by using an antireceptor antibody-photosensitizer fusion protein. Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9221-5. doi: 10.1073/pnas.0904140106.
•‎ Shramova EI, Shilova MV, Ryabova AV, Dzhalilova DS, Zolotova NA, Telegin GB, Deyev SM, Proshkina GM. Barnase*Barstar-guided two-step targeting approach for drug delivery to tumor cells in vivo. J Control Release. 2021 Dec 10;340:200-208. doi: 10.1016/j.jconrel.2021.11.001.

Премии и награды

•‎ Медаль ордена «За заслуги перед Отечеством» II степени, 2018 г.
•‎ Премия РАН имени М.М. Шемякина, 2016 г.
•‎ Премия РАН имени И.И. Мечникова, 2014 г.
•‎ Медаль и диплом Европейской научно-промышленной палаты, 2012 г.

Персональные профили исследователя

•‎ Web of Science: F-8191-2014.
•‎ Scopus: 6603799895.
•‎ РИНЦ: SPIN-код: 2562-1845, AuthorID: 81567.
•‎ ORCID: 0000-0002-3952-0631.