Научные интересы

Молекулярная биология прокариот. Механизмы регуляции экспрессии генов. Горизонтальный перенос генов. Генетическая инженерия бактерий. Программируемые нуклеазы.

Персональные профили исследователя

Web of Science ResearcherID: P-5401-2016
Scopus Author ID: 6603318679
ORCID ID: 0000-0002-2292-6424

Научные публикации

1. Prostova M, Shilkin E, Kulikova AA, Makarova A, Ryazansky S, Kulbachinskiy A. 2022. Noncanonical prokaryotic X family DNA polymerases lack polymerase activity and act as exonucleases. Nucleic Acids Res. 50(11):6398-6413.
   

2. Agapov A, Olina A, Kulbachinskiy A. 2022. RNA polymerase pausing, stalling and bypass during transcription of damaged DNA: from molecular basis to functional consequences. Nucleic Acids Res. 50(6):3018-3041.
   

3. Kropocheva E, Kuzmenko A, Aravin AA, Esyunina D, Kulbachinskiy A. 2021. A programmable pAgo nuclease with universal guide and target specificity from the mesophilic bacterium Kurthia massiliensis. Nucleic Acids Res. 49(7): 4054-4065.
   

4. Oguienko A, Petushkov I, Pupov D, Esyunina D, Kulbachinskiy A. 2021. Universal functions of the σ finger in alternative sigma factors during transcription initiation by bacterial RNA polymerase. RNA Biol. 18(11):2028-2037.
   

5. Kuzmenko A, Oguienko A, Esyunina D, Yudin D, Petrova M, Kudinova A, Maslova O, Ninova M, Ryazansky S, Leach D, Aravin AA, Kulbachinskiy A. 2020. DNA targeting and interference by a bacterial Argonaute nuclease. Nature 587 (7835): 632-637.
   

6. Agapov A., Ignatov A., Turtola M., Belogurov G., Esyunina D., Kulbachinskiy A. 2020. Role of the trigger loop in translesion RNA synthesis by bacterial RNA polymerase. J. Biol. Chem. 295(28):9583-9595. doi: 10.1074/jbc.RA119.011844.
   

7. Olina A., Kuzmenko A., Ninova M., Aravin A.A., Kulbachinskiy A., Esyunina D. 2020. Genome-wide DNA sampling by Ago nuclease from the cyanobacterium Synechococcus elongatus. RNA Biol. 17(5): 677-688.
   

8. Kuzmenko A., Yudin D., Ryazansky S., Kulbachinskiy A., Aravin A.A. 2019. Programmable DNA cleavage by Ago nucleases from mesophilic bacteria Clostridium butyricum and Limnothrix rosea. Nucleic Acids Res. 47(11): 5822-5836.
   

9. Ryazansky S., Kulbachinskiy A., Aravin A.A. 2018. The Expanded Universe of Prokaryotic Argonaute Proteins. MBio 9(6). pii: e01935-18.
   

10. Lisitskaya L, Aravin AA, Kulbachinskiy A. 2018. DNA interference and beyond: structure and functions of prokaryotic Argonaute proteins. Nat Commun. 9(1):5165.
    

Награды и премии

Медаль Российской академии наук с премией для молодых ученых, 2009 г.