Научные интересы

Nсследование белков и пептидов, включенных в процессы трансмембранной передачи сигналов, дифференцировки и апоптоза клеток.

Научные публикации

Shemykin MM, Ovchinnikov YuA, Kiryushkin AA, Vinogradova EI, Miroshnikov AI, Alakhov YuB, Lipkin VM, Shvetsov YuB, Wulfson NS, Rosinov BV, Bochkarev VN, Burikov VM. Mass spectrometric determination of the amino-acid sequence of peptides. Nature, 1966, 211:361-366
Ovchinnikov YuA, Monastyrskaya GS, Gubanov VV, Guryev SO, Salomatina IS, Shuvaeva TM, Lipkin VM, Sverdlov ED. The primary structure of E.coli RNA polymerase. Nucleotidesequence of the rpoC gene and amino acid sequence of the β’-subunit. Nucleic Acids Research, 1982, 10:4035-4044
Lipkin VM, Khramtsov NV, Vasilevskaya IA, Atabekova NV, Muradov KG, Gubanov VV, Li T, Johnson JP, Volpp KJ, Applebury ML. The β-subunit of bovine rod photoreceptor cGMP phosphodiesterase. Comparison with the phosphodiesterase family. J Biol Chemistry 1990, 265:12955-12959
Lipkin VM, Obukhov AN. Structure and mechanisms of function of visual system proteins. Membrane Cell Biology, 2000, 13:165-193.
Navolotskaya EV, Zargarova TA, Malkova NV, Krasnova SB, Zav'yalov VP, Lipkin VM. -Endorphin-like peptide SLTCLVKGFY is a selective agonist of nonopioid -endorphin receptor. Biochemical and biophysical research communications, 2002, 292:799-804.
Zhokhov SS, Kostanyan IA, Gibanova NV, Surina EA, Storozheva ZI, Proshin AT, Lipkin VM. Hexapeptides TGENHR and TQVEHR induce leukemia cell differentiation and exhibit neuroprotective properties. J. Peptide Science, 2004, 10:174.
Rzhevsky DI, Zhokhov SS, Babichenko II, Goleva AV, Goncharenko EN, Baizhumanov AV, Murashev AN, Lipkin VM, Kostanyan .A. HLDF-6 peptide effects behavior reactions and organism functions dependent on androgen hormones in normal and castrated male mice. Regulatory peptides, 2005, 127:111-121.
Navolotskaya EV., Kovalitskaya YuA., Sadovnikov VB., Zolotarev YuA., Kolobov AA., Yurovsky VYu, Lipkin VM. SyntheticACTH-like peptide GKVLKKRR, corresponding to the fragment 81-88 of human Pro-interleukin-1α, acts as an antagonist of ACTH receptor. International J. of Peptide Research and Therapeutics, 2008, 14:10-15.
Bogachouk AP, Storozheva ZI, Solovjeva OA, Sherstnev VV, Zolotarev YA, Azev VN, Rodionov IL, Surina EA, Lipkin VM (2016). Comparative study of the neuroprotective and nootropic activities of the carboxylate and amide forms of the HLDF-6 peptide in animal models of Alzheimer's disease. J Psychopharmacol 30 (1), 78–92
Navolotskaya EV, Lipkin VM, Садовников ВБ, Zavyalov Petrovich (2019). Cholera Toxin B Subunit and Peptide LKEKK Inhibit TNF-α Signaling in Intestinal Epithelial Cells and Reduce Inflammation in a Mouse Model of Colitis. J Clin Exp Immunol 4 (4), 1–6

Премии и награды

Премия Ленинского комсомола, 1975
Орден Дружбы народов, 1981
Государственная премия СССР в области науки и техники, 1982
Премия РАН имени Ю. А. Овчинникова, 1997

Персональные профили исследователя

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