Научные интересы

Молекулярные и клеточные механизмы формирования ранних и отдаленных эффектов воздействия ионизирующего излучения. 

Биологические эффекты пролонгированного и хронического облучения. Механизмы репарации ДНК. Количественный и качественный анализ повреждений ДНК.

Научные публикации

•‎ I.V. Ozerov, K.V. Lezhnina, E. Izumchenko, A.V. Artemov, S. Medintsev, Q. Vanhaelen, A. Aliper, J. Vijg, A.N. Osipov, I. Labat, M.D. West, A. Buzdin, C.R. Cantor, Y. Nikolsky, N. Borisov, I. Irincheeva, E. Khokhlovich, D. Sidransky, M.L. Camargo, Zhavoronkov A. In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development. // Nature Communications. 2016. V.16. № 7. e13427. doi: 10.1038/ncomms13427.
•‎ A.N. Osipov, M. Pustovalova, A. Grekhova, P. Eremin, N. Vorobyova, A. Pulin, A. Zhavoronkov, S. Roumiantsev, D.Y. Klokov, I. Eremin Low Doses of X-rays Induce Prolonged and ATM-independent Persistence of γH2AX Foci in Human Gingival Mesenchymal Stem Cells. // Oncotarget. 2015. V. 6. No. 29. P. 27275-27287. doi:10.18632/oncotarget.4739.
•‎ A.N. Osipov, A. Grekhova, M. Pustovalova, I.V. Ozerov, P. Eremin, N. Vorobyeva, N. Lazareva, A. Pulin, A. Zhavoronkov, S. Roumiantsev, D. Klokov, I. Eremin Activation of homologous recombination DNA repair in human skin fibroblasts continuously exposed to X-ray radiation. // Oncotarget. 2015. V. 6. No. 29. P. 26876-26885. doi:10.18632/oncotarget.4946.
•‎ M. Pustovalova, Т.A. Astrelina, A. Grekhova, N. Vorobyeva, A. Tsvetkova, T. Blokhina, V. Nikitina, Y. Suchkova, D. Usupzhanova, V. Brunchukov, I. Kobzeva, Т. Karaseva, I.V. Ozerov, A. Samoylov, A. Bushmanov, S. Leonov, E. Izumchenko, A. Zhavoronkov, D. Klokov, A.N. Osipov Residual γH2AX foci induced by low dose x-ray radiation in bone marrow mesenchymal stem cells do not cause accelerated senescence in the progeny of irradiated cells. // Aging (Albany NY). 2017. V. 9. No. 11. P. 2397-2410. doi: 10.18632/aging.101327.
•‎ M. Sorokin, R. Kholodenko, M. Suntsova, G. Malakhova, A. Garazha, I. Kholodenko, E. Poddubskaya, D. Lantsov, I. Stilidi, P. Arhiri, A. Osipov, A. Buzdin Oncobox Bioinformatical Platform for Selecting Potentially Effective Combinations of Target Cancer Drugs Using High-Throughput Gene Expression Data. // Cancers. 2018. V. 10. No. 10. e365. // https://doi.org/10.3390/cancers10100365
•‎ A.M. Aliper, M.E. Bozdaganyan, P.S. Orekhov, A. Zhavoronkov, A.N. Osipov Replicative and radiation-induced aging: a comparison of gene expression profiles. // Aging (Albany NY). 2019. V. 11. No. 8. P. 2378-2387. https://doi.org/10.18632/aging.101921
•‎ M. Pustovalova, A. Grekhova, Т. Astrelina, V. Nikitina, E. Dobrovolskaya, Y. Suchkova, I. Kobzeva, D. Usupzhanova, N. Vorobyeva, A. Samoylov, A. Bushmanov, I.V. Ozerov, A. Zhavoronkov, S. Leonov, D. Klokov, A.N. Osipov Accumulation of spontaneous γH2AX foci in long-term cultured mesenchymal stromal cells. // Aging (Albany NY). 2016 . V. 8. Issue 12. P. 3498-3506. doi: 10.18632/aging.101142.
•‎ A.N. Osipov, N.M. Smetanina, M.V. Pustovalova, E. Arkhangelskaya, D. Klokov The formation of DNA single-strand breaks and alkali-labile sites in human blood lymphocytes exposed to 365nm UVA radiation. // Free Radical Biology & Medicine. 2014 May 9. V. 73. P. 34-40. doi: 10.1016/j.freeradbiomed.2014.04.027
•‎ F. Cortese, D. Klokov, A. Osipov, J. Stefaniak, A. Moskalev, J. Schastnaya, C. Cantor, A. Aliper, P. Mamoshina, I. Ushakov, A. Sapetsky, Q. Vanhaelen, I. Alchinova, M. Karganov, O. Kovalchuk, R. Wilkins, A. Shtemberg, M. Moreels, S. Baatout, E. Izumchenko, J.P. de Magalhães, A.V. Artemov, S.V. Costes, A. Beheshti, X.W. Mao, M.J. Pecaut, D. Kaminskiy, I.V. Ozerov, M. Scheibye-Knudsen, A. Zhavoronkov Vive la radiorésistance!: converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization. // Oncotarget. 2018. V. 9. No. 18. P. 14692-14722. https://doi.org/10.18632/oncotarget.24461
•‎ N. Babayan, N. Vorobyeva, B. Grigoryan, A. Grekhova, M. Pustovalova, S. Rodneva, Y. Fedotov, G. Tsakanova, R. Aroutiounian, A. Osipov Low repair capacity of DNA double-strand breaks induced by laser-driven ultrashort electron beams in cancer cells. // International Journal of Molecular Sciences. 2020. V. 21. № 24. pii: 9488. doi:10.3390/ijms21249488.

Персональные профили исследователя

Web of Science: G-4791-2010.
Scopus: 55736694700.
РИНЦ: 95135.
ORCID: 0000-0001-5921-9056.